On the Leap Pad 2, I was trying to find a way to remove all of the profile information on the home screen. It is too easy for the kids using it to create new profiles and all the junk inside those profiles.
The trick is to hit the Home button and the Volume up button at the same time.
This enters you enter the parent settings menu where you can have more admin control over the content on the leap pad. The profiles can easily be deleted here and you can turn off some of the annoying stuff.
I thought you would be able to do this from the leap frog application but I wasn't able to find it easily.